Which act required labeling of selected dangerous and addictive substances and identified USP and NF as official standards?

• A. Pure Food and Drug Act 1906
• B. Food Drug and Cosmetic Act 1938
• C. Kefauver-Harris Amendments 1962
• D. Drug Importation Act 1848

Answer: (A)

The question tests how early federal regulation began shaping drug labeling and quality standards. The Pure Food and Drug Act of 1906 required truthful labeling for certain dangerous and addictive substances and designated the United States Pharmacopeia and National Formulary as the official standards of strength and purity for drugs. This established a formal reference for quality control that regulators and manufacturers could rely on, paving the way for later safety and labeling requirements. The other acts address different aspects—such as safety testing before marketing or drug import controls—without the combination of mandated labeling for selected substances and formal adoption of USP/NF as official standards.