DEA Form 222 is used to order which substances?

• A. Schedule III and IV
• B. Non-controlled prescription medications
• C. All controlled substances
• D. Schedule I and II controlled substances

Answer: (C)

DEA Form 222 is the official order document used for controlled substances, but it is limited to the most tightly regulated categories. In practice, it is used to order Schedule I and Schedule II controlled substances, such as morphine or other tightly controlled opioids, as well as drugs with high abuse potential that have strict procurement controls. Substances in Schedule III to V, as well as non-controlled medications, are not ordered with this form; these can be obtained through other authorized methods, like electronic ordering systems or standard invoices.

So, the form’s purpose is to control the ordering of the highest-risk substances (Schedule I and Schedule II), not all controlled substances.